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The spatial distribution and intracellular localization of these microbes can be mapped for more precise prognostication and tailored treatment strategies in clinical settings, ultimately improving cancer management

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ROS production in the mitochondria has been shown to be the signalling pathway that regulates the immune response and autophagy but is also important for the induction of ferroptosis [41, 42]

therefore, it can exert a therapeutic effect through intestinal pathways

10.12659/MSM.930001 Med Sci Monitor

A unifying feature is their ability to mitigate oxidative stressfor example, many flavonoids, alkaloids, and saponins activate the Nrf2/ARE pathway, upregulating endogenous antioxidant enzymes (such as superoxide dismutase and glutathione peroxidase) to neutralize excess reactive oxygen species (Wang Q