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Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

doi:10.1016/j.otc.2019.09.010 Gupta RJ, Kademani D, Liu SY

The answer is not the mcg number

Cancer Chemother Pharmacol Ther 44(5):411416 Jiang J et al (2019) Combretastatin A4 nanodrug-induced MMP9 amplification boosts tumor-selective release of doxorubicin prodrug

The absence of a plausible interaction mechanism no CYP450 involvement, no blood-sugar effects, and poor oral bioavailability means the theoretical risk is low