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HTLV-1 is not very dominant and known in India, but there has been a recent increase in ATL cases in a tertiary healthcare center in northern Kerala

Both infected cells crossing the compromised blood-brain barrier and virions and exosomes containing viral genetic material can activate microglia via TLR3 and TLR2 receptors (191, 194)

These alterations impair NRF2 degradation and result in sustained activation of its transcriptional program

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