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Using SERMs or aromatase inhibitors can mitigate this

By controlling T cell metabolic pathways like glycolysis, OXPHOS, FAO, and amino acid metabolism, these tactics may effectively regulate T cell differentiation, function, and immune response, offering a fresh approach to the treatment of autoimmune diseases ( Figure 3 )

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Common side effects include: Weight gain Nausea or vomiting Diarrhea Asthma or breathing problems Hair whitening or loss Skin rashes Hives or allergic reactions Rare severe reactions like toxic epidermal necrolysis or Steven-Johnson syndrome (with higher doses) Always consult with a qualified practitioner to minimize the risk of side effects