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Description

Astrocytes as drivers and disruptors of behavior: new advances in basic mechanisms and therapeutic targeting

TABLE 1 The regulatory small molecule compounds of targeting System X c /GSH/GPX4 axis in ferroptosis

During tumor progression, macrophage-derived TGF-1 can inhibit transcription through SMAD signaling, thereby promoting ferroptosis (85) and thus representing a complex interplay between immunosuppressive cytokines and ferroptotic mechanisms