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This dual dysfunction of microglia and astrocytes leads to extensive oxidative stress, immune activation, and eventual neuronal degradation

The severe form of this disorder is characterized by a number of unusual biochemical features

Mol Cancer Ther 11(6):12691278 Kitano Y, Baba Y, Nakagawa S et al (2018) Nrf2 promotes oesophageal cancer cell proliferation via metabolic reprogramming and detoxification of reactive oxygen species

Administered appropriately, under professional supervision, glutathione replenishment can restore cellular health, thus improving a patients overall health, with very few (if any) downsides

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