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The uptake through this mechanism is maximized by providing a high concentration gradient and avoiding the presence or production of transport inhibitors, such as ophthalmic acid

Genetic tests were not performed by the investigators to confirm exclusion diagnostics

Nonetheless, the high absorbance intensities indicate that a comparatively high proportion of AgNO 3 was reduced to the consistent AgNP concentrations, suggesting that the method is suitable for high-throughput synthesis

While the therapy is still undergoing clinical evaluation, the success of these early treatments signals a transformative future in diabetes care

These suggest that regulating the abnormal metabolism of liver tumor cells and firing up TME to turn cold tumor into hot tumor are potential strategies to improve the therapeutic effect of ICIs in liver tumor