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Steinbrecher et al

A short doubling time indicates that the deaths are all bunched together, and a long doubling time indicates that the deaths are spread out over a broader range of ages

Tavallaie S

In addition to its effect on LSC drug efficacy, phenotypic analysis of KG-1a AML cells treated with PL for 48 h in vitro revealed loss of the AML stem/progenitor markers CD34 and CD123, as well as the myeloid marker CD13, at all concentrations tested (5, 10 and 20 M) (Fig