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In recent research, impairment of mitochondrial functionality was found in humans with MDD, such as lowered respiration and ATP-related oxygen consumption (Kuffner et al., 2020)

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Zou J, Li Y, Liao N, Liu J, Zhang Q, Luo M

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By highlighting both the complex synthesis challenges and the latest solutions for enhancing its pharmaceutical properties, this review offers a more comprehensive and forward-looking perspective on curcumins evolution from traditional medicine to modern therapeutics

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The final step of production occurs in the liver, where enzymes oxidize TMA into TMAO

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