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Hu, J, Yang, Q, Zhang, W, Du, H, Chen, Y, Zhao, Q, Dao, L, Xia, X, Fowlkes, NW, Zhang, Z, Mahadeo, KM, Gorlick, R, Kopetz, S , Dotti, G, Li, S

Mitochondria are cholesterol-poor organelles compared to plasma membrane, and this regulated transport of cholesterol in mitochondria plays physiological role in the synthesis of bile acids in liver and steroidogenic hormones in other tissues

Lage R, Diguez C, Vidal-Puig A, Lpez M

248 Also, SAM has a key role in regulating liver homeostasis, and reduced levels of SAM synthesis have been detected in various chronic liver injuries, such as NAFLD