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Doses above 100mg per day have been explored in animal models but show diminishing returns in human observational data

Whether driven by osteoarthritis, repetitive strain, or acute injury, inflammatory mediators within the joint capsule accelerate cartilage breakdown and sensitize pain receptors

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Wang K, et al

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Statistical analysis Data are represented as mean SEM of at least three independent experiments