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Moisture can promote hydrolysis (chemical breakdown due to water), and oxygen may contribute to oxidation in susceptible peptide sequences (Sigma-Aldrich, 2023b)

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For patients and clinicians who have followed the peptide regulatory saga since 2023, this announcement carries weight

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Plastic changes induced by either high-frequency tetanization combined with depolarization of the recorded interneuron (Cowan et al., 2001) were prevented by adding BAPTA to the intracellular pipette solution