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A compromised intestinal barrier, or leaky gut, may allow microbial products to enter systemic circulation, triggering neuroinflammation and contributing to multi-organ dysfunction [123]

[DOI] [PubMed] [Google Scholar] 328.Dardiotis E., Tsouris Z., Mentis A.A., Siokas V., Michalopoulou A., Sokratous M., Dastamani M., Bogdanos D.P., Deretzi G., Kountouras J

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Studies have demonstrated that garlic extracts, particularly the water fraction, can ameliorate allergic airway inflammation by reducing inflammatory cell infiltration and mucus hypersecretion, as well as modulating cytokine profiles to favor anti-inflammatory responses [221]

The operational multiple dosing half-life: a key to defining drug accumulation in patients and to designing extended release dosage forms

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