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They worked with locked nucleic acid (LNA) gapmers to knock down DUX4 pre-mRNA [207, 208]

At the same concentration of 580 M, Cu(OAc) 2 induced a higher upregulation of IL-1 than CuCl 2 , while CuCl 2 induced a higher upregulation of IL-8, HSPA1A and FOSL1 than Cu(OAc) 2

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However, both pre- and post-treatment with the anthocyanin-enriched fraction avoided these post-translational modifications (Figure 6B)

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