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The addition of antioxidants partially restores antitumor immunity, by enhancing function of chronically stimulated CD8 + T cells (64, 128)

Since the major quinone forms found in the cells, ubiquinone and plastoquinone, are located into membranes and do not have electrophilic carbon groups that could be substituted by GSH, the question of the GHR physiological substrates is still open