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Mitochondria Most (90%) of the cytosolic TPP is transported into mitochondria via the mitochondrial thiamine pyrophosphate transporter [MTPPT, product of the SLC25A19 gene (56)]

Glutathione shifts the process of melanogenesis from eumelanin to pheomelanin through the reaction between thiol and dopaquinone groups causing formation of sulfhydryl-dopa conjugates[] [Figure 2]

The applications of miRNAs analogue or anti-miRNAs have shown compelling outcomes in-vitro and in-vivo cancer studies, suggesting the miRNA-based drugs are emerging as a novel strategy for cancer therapy

In the dura mater and other regions supplied by the trigeminal nerve, this results in neurogenic inflammation due to excessive vasodilation, mast cell degranulation, plasma protein extravasation, and the release of inflammatory mediators such as serotonin

doi:10.3950/jibiinkoka.92.694 Kinishi M, Amatsu M, Hosomi H

Yousefi-Ahmadipour A, et al