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Notably, cyclic AMP (cAMP) activation is known to either inhibit or activate ERK in a cell type-specific manner [46, 47]

347,348 Uncoupling of astrocytic syncytia or knocking out Cx43 in experimental models instigates seizures

For example, it is possible that plant flavonoids with antioxidant properties could block ROS, prevent oxidative stress, and resulting inflammatory processes, mutagenesis, apoptosis, and arrest cell cycle (81, 83)