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Viral infection of astrocytes resembles reactive astrogliosis with elevated type-I IFN production, increased inflammation, and down-regulation of transporters for water, ions, choline, and neurotransmitters 312

and Thapa Shrestha, U

Eur J Pediatr

In DFU, notch pathway dysfunction can lead to inhibition of cell differentiation, proliferation disorders, and reduced angiogenesis, all of which interfere with diabetic wound healing

Daily transient coating of the intestine leads to weight loss and improved glucose tolerance

Obviously, more studies are needed to sort out molecular mechanisms involved in the transcriptional/posttranscriptional and/or posttranslational regulation of these antioxidant enzymes in vitro and in vivo