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Although this metabolic pathway has been more extensively studied in tissues such as the liver, the unique high CYP1B1 environment in fibroid tissue suggests that local metabolism of E may constitute an intrinsic source of ROS [46]

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10.1182/blood.2019000944 Blood

Heylen E, Verstraete P, Van Aerschot L, Geeraerts SL, Venken T, Timcheva K, et al

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K., Muir, A., Weissman, J