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Description

Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations

Those in need of prevention include those vulnerable to a disease or condition and those to be prevented

Ramani N, Gu J, Aung P, Sfamenos S, Sdringola-Maranga C, Nagarajan P, Tetzlaff MT, Curry JL, Ivan D, Diab A, Hwu W, Prieto VG, Torres-Cabala CA

Biol Trace Elem Res 173(1):132139

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It has been shown that low CD74/high M2 signature is linked to increased tumor aggressiveness, while CD74 expression, associated with M1 macrophages, correlates with longer patient survival (62)