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The translocation of phospholipids in cellular membranes, for example, PS exposure on the cell surface and cardiolipin translocation within the mitochondrial membranes, are key events in the initial phases of apoptosis and correlate with other major hallmarks of dying cells that include plasma membrane blebbing, cell shrinkage, loss of mitochondrial membrane potential, caspase activation, chromatin condensation, DNA fragmentation, and cytoskeleton remodeling

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Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis

Nat Med (1996) 2:5515