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10.1111/j.0959-9673.2005.00428.x 241 TellerJ

Dr Grimaldi is Practice Principal of PhysioTec Physiotherapy in Brisbane and an Adjunct Senior Research Fellow at the University of Queensland

Statements Author contributions ZWL: Writing original draft

Science 337 (6101): 14711473

To prolong the prognosis of patients with advanced HCC who receive sequential treatment with systemic agents, it is important to start systemic therapy with good liver function at induction and maintain good liver function during treatment by appropriately managing adverse events