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Our study elucidates a crucial microbial-host interaction within the tumor microbiome, enabling the precise administration of targeted prodrugs

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Hoshimoto S, Takeuchi H, Ono S

In separate assays, serum-starved PC3 cells were transfected with AR-Flag variant 2 and pmCherry or pmCherry-RanQ69L and treated with Sema4D-Fc (2 g/ml, Bio-techne), DHT (Sigma) or vehicle control for 1.5 h or 1 h respectively