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To achieve this, these enzymes can bind non-substrate ligands (ligandin function) and/or catalyze the conjugation of glutathione onto the targeted molecules, the latter activity being exhibited by GSTs having a serine or a tyrosine as catalytic residues

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Together with a small quantity in the ovary and gastrointestinal (GI) tract, its significant amount is found in the bone marrow, cerebral fluid, and bile juice

For gut-targeted applications leaky gut, IBD, gastric repair oral BPC-157 may actually be superior, because it delivers high concentrations directly to the target tissue