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Description

Essential Principle 12.1 was amended to clarify already exisiting requirements for cyber security, data and information management, and requirements related to development, production, and maintenance

Stechmiller, J

Evidence for the latter was generated in the SHMT2 knockdown (KD) model where a decrease in the one carbon unit pool, as well as an accumulation of metabolites upstream the de novo purine synthesis was observed ( de novo purine synthesis and increased DNA damage