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doi:10.1093/ilar.46.2.83

In order to demonstrate potential for biological applications, along with compatibility with longer peptides, an i,i + 4 stapled analog of the 11-mer linear peptide ligand that binds the co-activator binding site of estrogen receptor was synthesized

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The core functions of astrocytes include controlling the homeostasis of neurotransmitters (through uptake, catabolism and the supply of precursors), K + buffering, metabolic support, scavenging of reactive oxygen species (ROS), regulation of water transport and interstitial fluid, formationthrough perivascular endfeetof the parenchymal component of the bloodbrain barrier (glia limitans perivascularis), contribution to chemosensing, regulation of energy homeostasis, participation in transmitophagy, and many other processes 14