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Our results suggest potential options for enhancing the therapeutic efficacy of acne treatment

Competing interests The authors declares that he have no competing interests

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In summary, this glycolysis-centered metabolic reprogramming not only provides essential energy for the abnormal proliferation of leiomyoma cells but also influences the physiological state of surrounding tissues by altering the metabolic microenvironment (such as acidification and lactate signaling), constituting a key mechanism for the sustained growth of uterine fibroids