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Supplementation with L-cysteine has been shown to not only increase glutathione levels, but to also upregulate the expression of vitamin D binding proteins, receptors, and enzymes that results in increased vitamin D levels

Non-glutathione disulfide substrates that employ monothiol mechanism (iii) should not be trapped as Grx(SSR) intermediates, which might explain the rather small number of verified non-glutathione disulfide substrates of glutaredoxins to date

Obviously, there is not a definite translation between mice and humans but the results are certainly worth keeping in mind

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Of note, artificial ECMs, including the collagenbased ones, have been employed to promote guided nerve regeneration (Georgiou et al., 2013

Biometals 38 , 711736 (2025)