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Although there is disagreement in affirming it is an etiological factor, what is undeniable is that this is a contributor to the BD clinical presentation and increases the risk of cognitive deterioration [47]

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Hypothetical Molecular Mechanisms Underlying Hyperhomocysteinemia-Mediated Vascular Disorders Hyperhomocysteinemia-Mediated Oxidant Stress through Imbalanced Thiol Redox Status Numerous studies indicate that oxidant stress plays a role in the development of occlusive atherosclerotic lesions that are observed primarily in homozygotes for the CBS defect (McCully, 1983) and later in experimental hyperhomocysteinemia

10.1080/14786419.2023.2269465 Summary Keywords organosulfur compounds, garlic, atherosclerosis, lipid metabolism, oxidative stress, anti-Inflammatory agents, endothelial protection, PCSK9 inhibitors Citation Tang Y, Lv D, Tao Y and Wang J (2025) The therapeutic effects of natural organosulfur compounds on atherosclerosis and their potential mechanisms: a comprehensive review