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This lack of effect on ACTH and cortisol plasma levels was evident even at doses more than 200-fold higher than the ED50 for GH release

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References [1] Sen,CK

In contrast, ritonavir is likely to compete with GSSG for binding at the same P-pocket of the Mrp1 binding site, thereby inhibiting the binding and the subsequent transport of this Mrp1 substrate (Figs