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doi: 10.1016/j.micpath.2017.12.005

One study reported that ALS patients had signs of intestinal inflammation and dysbiosis with a shift toward microbes that can induce oxidative stress and reduce gut barrier function [214]

It often occurs while you are sleeping as well

[DOI] [PMC free article] [PubMed] [Google Scholar] Sethi A, Wordinger RJ, Clark AF (2013) Gremlin utilizes canonical and non-canonical TGF signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells