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Elimination The apparent population mean clearance of tirzepatide is 0.061 L/h with an elimination half-life of approximately 5 days, enabling once-weekly dosing

Duration of Use Phentermine is generally prescribed for short-term use, usually up to 12 weeks, due to its potential for dependence and side effects

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It may also affect kidney function and carries cardiovascular risks with prolonged use, particularly in susceptible individuals