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SandbornWJColombelJFEnnsRFeaganBGHanauerSBLawranceICet alNatalizumab induction and maintenance therapy for Crohns disease

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However, the patient was always bright and positive about treatment, which left a strong impression

In contrast, lower than normal [ 14 C]-propionate or [ 14 C]- N 5 -methyl-tetrahydrofolate incorporation after fusion of cell lines with polyethylenglycol confirms that the two patients possess the same genetic defect (Watkins and Rosenblatt, 2013)

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The timeframe for observing results also plays a role short-term effects might call for a single, higher dose, while long-term studies may benefit from smaller, repeated doses