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Discussion Testicular ischemia induces germ cell apoptosis because of hypoxia and intracellular ATP depletion, and metabolic imbalance promotes the accumulation of harmful metabolites

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Initiation of the chain reaction of lipid peroxidation requires the spark provided by the reduction of Fe +3 to Fe +2 using a single electron provided by the O 2 - (superoxide anion radical) formed during oxidative respiration in mitochondria