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Synaptic plasticity alone would appear to be insufficient for long-term spatial memory formation given the impairment observed in MyRF / mice

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Flow cytometry analysis (Fig

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The measured effect on systemic vascular resistance may be an artifact due to the effect of increased left-to-right shunting on the mixed oxygen saturation (sampled using a pulmonary artery catheter): Pulmonary vasodilation decreases the right-sided pressures, which causes an increased left-to-right flow of blood through the shunt