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Metformin, commonly used in diabetes management, has been associated with reduced vitamin B12 absorption, potentially through effects on calcium-dependent vitamin B12-intrinsic factor absorption in the terminal ileum

[1][2][3] One of the sulfur-containing amino acids (along with cysteine and cystine), methionine is important (essential) to many bodily functions and must be directly consumed through supplementation or methionine-containing proteins

Typically, most supplements get lost in the digestive system, and very little gets absorbed by the body

PUBLIC HEALTH RELEVANCE: Cyanide poisoning has been recognized as a threat from smoke inhalation and potentially through weapons of mass destruction, but there are currently no methods available to rapidly detect cyanide in blood from at-risk patients

Comparison of the efficacy of parenteral and oral treatment for nutritional vitamin B12 deficiency in children

2010;299(3):R94552