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Since metabolites are the final downstream products of transcription and translation, they are closest to the phenotype ( To date, to identify biomarkers for the diagnosis and treatment response of MDD, lipids ( By profiling the serum metabolites of the patients with MDD and the control group, metabolites showing differences between the groups were identified as potential biomarkers

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Schooling CM, Lopez P, Yang Z, Zhao JV, Au Yeung SL, Huang JV

L-carnitine also plays a key role in the production of adenosine triphosphate (ATP) - the energy currency of the cell

Pathway analysis According to the metabolite set enrichment analysis of KOA and control SF samples, tryptophan metabolism, betaine metabolism, glutamate metabolism, cysteine metabolism, glycine and serine metabolism, glutathione metabolism, pantothenate and CoA biosynthesis, taurine and hypotaurine metabolism, methionine metabolism, and homocysteine degradation were the most disturbed pathways (Fig