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Physiology 25, 239249 10.1152/physiol.00011.2010 [DOI] [PubMed] [Google Scholar] Dammann O., Leviton A

To boost pegtibatinase stability and minimize unwanted protein aggregation, a cysteine-to-serine substitution at position 15 is introduced to prevent the formation of interdimer disulfide bonds

In summary, although current studies on ferroptosis in cerebral ischemia have identified key biological processes such as lipid peroxidation and iron metabolism imbalance, two central challenges remain unresolved

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