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Cell 68 , 879887 (1992)

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K562 cells were counted and resuspended at 1 10 6 live cells/mL and incubated with 5 M calcein AM for 1 h at 37C with mixing every 10 mins

Paeoniflorin suppresses neuronal ferroptosis to improve the cognitive behaviors in Alzheimers disease mice

Among the 38 hits from the screen, we selected the 15 with a stronger senolytic effect on etoposide-treated SK-MEL-103 cells and, taking advantage of inhibitors of apoptosis (emricasan) or ferroptosis (liproxstatin 1), assessed their mode of action (Fig