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Munyard, P

METTL1-mediated m7G tRNA modification promotes lenvatinib resistance in hepatocellular carcinoma

It requires a saliva collection of about 1 mL without bubbles upon morning waking within the first 5 minutes, the second sample also of 1 mL without bubbles at 30 minutes, and a third sample at 60 minutes

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This is a retrospective, single-center study, but real-life cohort data encompass a broader range of patients compared to randomized controlled studies, which often exclude individuals with various comorbidities