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These factors disrupt the delicate balance between the beneficial and harmful roles of lipids, leading to synaptic damage by impairing neurotransmitter release, synaptic plasticity, and membrane stability ( Table 3 )

During tumor cell biosynthesis, hexokinase II, involved in glycolysis, is highly expressed and can bind to voltage-dependent anion channels

Willemsen, J

[22] This modern biochemical research resulted in the identification of glutathione S -transferases in 1961, [23] followed by the discovery of cytochrome P450s in 1962, [24] and the realization of their central role in xenobiotic metabolism in 1963