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These advantages may include lower immunogenicity, higher loading capacity, and the potential to be engineered for targeted delivery and controlled release (147)

doi: 10.1016/j.krcp.2011.12.005 76 TonshoffBVeldhuisJDHeinrichUMehlsO

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In vitro quantification of the relative packaging efficiencies of single-stranded RNA molecules by viral capsid protein

Dose reduction should be done gradually and should be done under medical surveillance