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This is not only because smokers compensate by increasing inhalation leaving their smoke intake relatively unchanged, but also because a point is reached where reduced nicotine delivery meets with reduced consumer acceptance.[29] Dr Russells observations aside, there was little scientific support behind the idea that if nicotine could be successfully liberated from tobacco, the result could be a dramatic improvement in public health not least because substantial numbers of doctors believed nicotine caused cancer

Carter, Chris and Manners, Kim (2005)

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