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Several clinical characteristics were used to describe the sample and to explore their potential relationship with the samples smoking history

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Among studies examining the association of ECs with tobacco use initiation and use of other substances, as well as evidence of ECs as a smoking cessation strategy in adolescents, arranged from lower to higher quality in study design, there is one prospective cohort study 61 , 10 cross-sectional studies, and 14 longitudinal studies

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We examined changes in smoking-attributable mortality fractions as estimated by the Preston-Glei-Wilmoth method by age (ages 5085) across birth cohorts 18701965