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Closing, it must be understood that e-cigarettes can hugely benefit adult smokers, as long as they completely replace any other nicotine or tobacco products

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Data availability Data are unsuitable for public deposition due to ethical restrictions and legal framework of Japan

e-cigarette market, was not included in the 2018 study, the researchers decided to analyze some of its products for the current study

Artist's Description A stylized hand reaches for a cigarette next to an opened pack against a bright blue background

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