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This means that the system is particularly designed to be activated by aversive stimuli. To demonstrate this for nicotine, Liu and her colleagues infused the drug into mice and measured the second-by-second release of dopamine in the brain using a recently developed technique called dLight-based fiber photometry

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Borland R, Yong H, Wilson N, Fong G, Hammond D, Cummings K, Hosking W, McNeill A: How reactions to cigarette packet health warnings influence quitting: findings from the ITC Four-Country survey

Smoking itself is a risk factor for OSA

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The decision, technically called a Marketing Granted Order, allows ZYNs 20 products to be marketed in the US