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Nicotine, a main component of e-cigarette aerosol, has been reported to increase cisplatin resistance in oral, lung, and bladder cell lines by inhibiting cisplatin-induced apoptosis 28,54,55,56

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Moderate PA has been deemed to improve immune competence in a manner, and the mechanisms for the effect of moderate exercise on the reduction of URTI risk are still being explored and debated

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