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The two phases separate after extraction and an aliquot of the aqueous layer (water/acetonitrile/acetate buffer extract) was spiked with internal standard, extracted, centrifuged and analysed as per the pouch samples

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Bupropion remains a valuable alternative, particularly for smokers with comorbid depressive symptoms, whereas the limited impact of NRT highlights the importance of adherence and structured behavioral support

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In this study, the messages delivered by physicians regarding e-cigarettes in the most-watched electronic cigarette videos on YouTube in Trkiye were examined