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Curcumin significantly reduced depressive symptoms in chronic disease (SMD = 0.65, 95% CI: 1.16 to 0.13) and anxiety (SMD = 0.22, 95% CI: 0.40 to 0.05)

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374,454 Interestingly, subsequent studies revealed, nuclear factor erythroid 2-related factor 2 (NRF2) expression can be induced by HGF and EGF, activating the parkinsonism-associated deglycase ( Park ) gene

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