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At McKinney RSA, are seeing growing interest in developing and marketing oral products containing areca nutwhether alone or combined with tobacco or nicotine

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Nevertheless, concerns remain [3, 12], particularly around risks of vaping introducing youth to nicotine and cigarette use [13,14,15,16], though so far regular (at least weekly) vaping by youth in the UK has been rare [17, 18]

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"We respectfully disagree with the FDA's findings and decision and continue to believe we have provided sufficient information and data based on high-quality research to address all issues raised by the agency," the firm's chief regulatory officer, Joe Murillo, said in a statement